MIT Edgerton Center Protein Sets
  • Model of keratin coiled coil
  • MAST 2016 Teacher Workshop
  • Protein Booklet 1

Protein sets available December 2016!

Download the flyer about our PDF icon MIT Edgerton Center Protein sets.

Lesson Overview

Unlike most teaching aids, the MIT models are designed to teach what the molecules do, not just what molecules look like. These injection molded molecules are made to be manipulated.  In this way educators can teach abstract concepts in concrete ways.  

Students can build and fold proteins, learn about hydrophobic and hydrophilic interactions, demonstrate all 4 levels of protein structure, create models of proteins they know like hemoglobin and antibodies, and more. Diverse populations including English language learners, middle schoolers, and AP biology students all have found the learning experience interesting and memorable. Click here for information about the LEGO prototype versions of our DNA/RNA, Protein, and tRNA Sets.

The set contains:

-14 Protein kits

-14 Protein Booklet 1: Introduction to Structure and Function

-14 Protein Booklet 2: Advanced Protein Topics*

-14 Cell Membrane Mats

-14 Amylase Mats*

-14 Protein Card Packs

-Storage Crate

Note: The MIT Edgerton Center Protein Sets will not be available until December 2016. Please visit the DNA/RNA Sets page for information about sets available now. If you'd like to register your interest in the Protein sets, please contact or fill out the interest form.  Note that the Safari browser may not correctly display the form. Please use Chrome, Firefox, or Internet Explorer instead.

Informational Video

This video shows student and teacher workshops using our LEGO prototype sets: DNA/RNA, Protein, and tRNA.

Teacher Resources

MIT Edgerton Center Protein Teacher Guide coming soon!

For additional resources, visit our LEGO prototype sets webpage


Student Booklets and Laminates

Click below to see samples of our booklets and laminated materials:

RCSB Protein Data Bank

The RCSB Protein Data Bank has an extensive educational online resource, PDB-101.  PDB-101 is an online portal for teachers, students, and the general public to promote exploration in the world of proteins and nucleic acids. Learning about the diverse shapes and functions of these biological macromolecules helps to understand all aspects of biomedicine and agriculture, from protein synthesis to health and disease to biological energy.  

The RCSB PDB Molecule of the Month by David S. Goodsell presents short accounts on selected molecules from the Protein Data Bank. Each installment includes an introduction to the structure and function of the molecule, a discussion of the relevance of the molecule to human health and welfare, and suggestions for how visitors might view these structures and access further details. This feature provides an easy introduction to the RCSB PDB for all types of users, but especially for teachers and students.  We frequently use Goodsell images in our booklets.

The Protein Data Bank also has an excellent introductory video on proteins that covers the same material as our booklets.

Star BioChem Software

  • Visit for many excellent worksheets on various protein topics, such as hemoglobin and sickle cell anemia, DNA glycosylases, and an introduction to basic macromolecules.  All worksheets guide students through use of the software from the beginning.

    Molecular Workbench Software

    The Molecular Workbench Activity, "From DNA to Proteins and Protein Folding," is online at

    The above link will take you to 11 interactive lessons about DNA and protein structure, protein synthesis and folding, and sickle cell disease. In this version, modified for MIT by the Concord Consortium, the colors on the screen will match the colors of the amino acids. Having the colors of the models be consistent across all the different multimedia representations can be very helpful.

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    • false for 11 interactive Molecular Workbench lessons
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    Contact us if you would like to learn about our next teacher workshop. 

    Models and Lessons created by Kathleen M. Vandiver.  Graphics by Amanda Mayer.  ©MIT. All rights reserved.